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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFC2
All Species:
50.91
Human Site:
Y42
Identified Species:
80
UniProt:
P35250
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35250
NP_002905.2
354
39157
Y42
E
L
P
W
V
E
K
Y
R
P
V
K
L
N
E
Chimpanzee
Pan troglodytes
XP_001149874
354
39149
Y42
E
L
P
W
V
E
K
Y
R
P
V
K
L
N
E
Rhesus Macaque
Macaca mulatta
XP_001082511
352
38844
Y40
E
L
P
W
V
E
K
Y
R
P
V
K
L
N
E
Dog
Lupus familis
XP_546916
352
38707
Y40
E
L
P
W
V
E
K
Y
R
P
V
K
L
N
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUK4
349
38706
Y37
E
L
P
W
V
E
K
Y
R
P
L
K
L
N
E
Rat
Rattus norvegicus
Q641W4
349
38638
Y37
E
L
P
W
V
E
K
Y
R
P
V
K
L
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516769
407
45006
Y95
L
R
P
V
V
E
K
Y
R
P
V
K
L
N
E
Chicken
Gallus gallus
P53033
359
39688
Y47
E
L
P
W
V
E
K
Y
R
P
L
K
L
C
E
Frog
Xenopus laevis
NP_001084837
348
38438
Y37
E
L
P
W
V
E
K
Y
R
P
L
K
L
N
E
Zebra Danio
Brachydanio rerio
NP_001013344
349
39005
Y37
E
L
P
W
V
E
K
Y
R
P
L
K
L
N
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P53034
331
37155
V31
P
V
K
F
K
E
I
V
G
N
E
D
T
V
A
Honey Bee
Apis mellifera
XP_623937
350
39000
Y42
H
L
P
W
I
E
K
Y
R
P
Q
V
F
S
D
Nematode Worm
Caenorhab. elegans
P34429
368
41157
Y35
N
L
P
W
V
E
K
Y
R
P
S
K
L
D
E
Sea Urchin
Strong. purpuratus
XP_790650
352
38724
Y39
E
M
P
W
V
E
K
Y
R
P
T
S
L
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40339
323
36131
L33
N
K
E
T
I
D
R
L
Q
Q
I
A
K
D
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98
93.5
N.A.
92.3
91.5
N.A.
76.6
87.7
86.4
82.7
N.A.
68.9
67.2
35
71.1
Protein Similarity:
100
99.7
98.8
96.6
N.A.
95.4
94.9
N.A.
81.5
91.6
91.5
88.4
N.A.
79.6
78.8
51.6
85.5
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
80
86.6
93.3
93.3
N.A.
6.6
53.3
80
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
80
93.3
100
100
N.A.
20
73.3
86.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
54.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
72.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
0
0
0
0
0
7
0
0
0
0
0
7
0
14
14
% D
% Glu:
67
0
7
0
0
94
0
0
0
0
7
0
0
0
74
% E
% Phe:
0
0
0
7
0
0
0
0
0
0
0
0
7
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
7
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
14
0
7
0
0
0
7
0
0
0
0
% I
% Lys:
0
7
7
0
7
0
87
0
0
0
0
74
7
0
0
% K
% Leu:
7
74
0
0
0
0
0
7
0
0
27
0
80
0
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
14
0
0
0
0
0
0
0
0
7
0
0
0
60
0
% N
% Pro:
7
0
87
0
0
0
0
0
0
87
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
7
7
7
0
0
0
0
% Q
% Arg:
0
7
0
0
0
0
7
0
87
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
7
7
0
14
0
% S
% Thr:
0
0
0
7
0
0
0
0
0
0
7
0
7
0
0
% T
% Val:
0
7
0
7
80
0
0
7
0
0
40
7
0
7
0
% V
% Trp:
0
0
0
80
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
87
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _